LIMITED PARTNERSHIPS ACT 1907

Notice is hereby given that Avlar BioVentures Fund II Limited Partnership—B (the “Partnership”), a limited partnership registered under the Limited Partnerships Act 1907 in England with number LP7709 hitherto subsisting between Avlar BioVentures Scottish Limited Partnership (as general partner) and Avlar I (General Partner) Limited, formerly known as Quantum Healthcare Fund (General Partner) Limited (as limited partner), has been dissolved with effect from 4 March 2003. For and on behalf of Avlar BioVentures Scottish GP Limited acting in its capacity as general partner of Avlar BioVentures Scottish Limited Partnership acting in its capacity as general partner of the Partnership. 4 March 2003.